Voriconazole inhibits fungal cytochrome P450-mediated 14α-sterol demethylation, an essential step in ergosterol biosynthesis.
Invasive aspergillosis,
Candidemia in non-neutropenic patients and
Candida infections, disseminated infections in skin and infections in abdomen, kidney, bladder wall and wounds
Voriconazole
Invasive aspergillosis,
Candidemia in non-neutropenic patients and
Candida infections, disseminated infections in skin and infections in abdomen, kidney, bladder wall and wounds.
Usage:
Loading dose: 6mg/kg BID
Maintenance dose: 3mg to 4 mg/kg BID
